Sp in Italian

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Sp by itself isn’t a standard Italian word; it’s usually an abbreviation whose meaning depends on context. Common possibilities:

S.p.A. = società per azioni (a joint-stock company; like “Inc.”/“PLC”)
sp. (lowercase, often in dictionaries/scientific names) = “species” (used when the exact species isn’t specified)
SpA = shorthand for the ankle joint (articolazione tibio-tarsica) in medical contexts
SP (road signs) = strada provinciale (provincial road)

If you share the full phrase/sentence, I can tell which one fits.